LUMI-NO (Nitric Oxide)
Nitric oxide (NO) is a ubiquitous signaling molecule important in cardiovascular disease, inflammation, cancer, neurodegeneration, pain, and other areas. Nitric oxide is generated from three nitric oxide isoforms, endothelial nitric oxide synthase (eNOS), inducible nitric oxide synthase (iNOS), neuronal nitric oxide synthase (nNOS), as well as through nitrite reduction. Signaling proceeds through canonical activation of soluble guanylyl cyclase (sGC) and non-canonical posttranslational modifications including S-nitroso formation.
Nitric oxide (NO) is a ubiquitous signaling molecule important in cardiovascular disease, inflammation, cancer, neurodegeneration, pain, and other areas. Nitric oxide is generated from three nitric oxide isoforms, endothelial nitric oxide synthase (eNOS), inducible nitric oxide synthase (iNOS), neuronal nitric oxide synthase (nNOS), as well as through nitrite reduction. Signaling proceeds through canonical activation of soluble guanylyl cyclase (sGC) and non-canonical posttranslational modifications including S-nitroso formation.
Nitric oxide (NO) is a ubiquitous signaling molecule important in cardiovascular disease, inflammation, cancer, neurodegeneration, pain, and other areas. Nitric oxide is generated from three nitric oxide isoforms, endothelial nitric oxide synthase (eNOS), inducible nitric oxide synthase (iNOS), neuronal nitric oxide synthase (nNOS), as well as through nitrite reduction. Signaling proceeds through canonical activation of soluble guanylyl cyclase (sGC) and non-canonical posttranslational modifications including S-nitroso formation.
FEATURES
TARGET: Nitric Oxide (NO)
SAMPLE: Buffered Systems, Plasma
SENSITIVITY: <25 nM (concentration of NO donor DEA NONOate)
RANGE: 25 nM–25 µM (concentration of NO donor DEA NONOate)
TESTS/KIT: 100 tests (96-well plate)
READOUT: Luminescence: open filter
PURPOSE: For Research Use Only. Not for use in diagnostic procedures