Peroxynitrite (ONOO−) is formed from the diffusion-limited reaction between nitric oxide and superoxide and mediates many negative effects in cardiovascular disease, inflammation, cancer, neurodegeneration, pain, and other areas. Peroxynitrite is a strong oxidant that can further decompose into highly reactive oxygen and nitrogen species that can damage DNA, nitrate proteins, oxidize lipids, and destroy invading pathogens.
Peroxynitrite (ONOO−) is formed from the diffusion-limited reaction between nitric oxide and superoxide and mediates many negative effects in cardiovascular disease, inflammation, cancer, neurodegeneration, pain, and other areas. Peroxynitrite is a strong oxidant that can further decompose into highly reactive oxygen and nitrogen species that can damage DNA, nitrate proteins, oxidize lipids, and destroy invading pathogens.
TARGET: Peroxynitrite (ONOO−)
SAMPLE: Live Cells, Buffered Systems
SENSITIVITY: <50 nM (bolus synthetic ONOO−)
RANGE: 100 nM – 100 µM (bolus synthetic ONOO−)
TESTS/KIT: 100 tests (96-well plate)
READOUT: Luminescence: open filter
PURPOSE: For Research Use Only. Not for use in diagnostic procedures.
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